Delayed initiation of antibiotic therapy is associated with worse outcomes in skin and soft tissue infections

1. Delayed initiation of antibiotic therapy was strongly associated with treatment failure and prolonged hospitalization in hospitalized SSTI patients. 2. Comorbidity burden and socioeconomic disparities significantly influenced SSTI outcomes, highlighting the importance of individualized management and antimicrobial stewardship. Evidence Rating Level: 3 (Average) In this prospective observational study, Biyazin et al. evaluated determinants of treatment